DSpace Community:http://dspace.bsuedu.ru/handle/123456789/462592026-04-05T18:01:05Z2026-04-05T18:01:05ZStudy of dose-dependent effect of 2-ethyl-6-methyl-3 hydroxypyridine succinate on the contractile function of isolated rat heatKesarev, O. G.Danilenko, L. M.Pokrovskii, M. V.Timokhina, A. S.Khavanskii, A. V.http://dspace.bsuedu.ru/handle/123456789/466002022-05-05T00:31:21Z2017-01-01T00:00:00ZTitle: Study of dose-dependent effect of 2-ethyl-6-methyl-3 hydroxypyridine succinate on the contractile function of isolated rat heat
Authors: Kesarev, O. G.; Danilenko, L. M.; Pokrovskii, M. V.; Timokhina, A. S.; Khavanskii, A. V.
Abstract: In experiments on the isolated rat heart there were studied the effects of different doses (21.43 mg/kg/day and 85 . 72 mg/kg/day) 2-ethyl-6-methyl-3 hydroxypy ridine succinate ("EkoPharmInvest", Russia), on the contractile function of isolated hearts subjected to prior doxorubicin model (20 mg/kg, intraperitoneal) of pathology. The dynamic of the power mechanisms of ion transport was evaluated by imposing high h eart rate (480 BPM) and increase concentration of Са2+ to 5 mmol in perfusate2017-01-01T00:00:00ZApproaches to antibiotic therapy in patients with calculous pyelonephritis, undergoing in-patient treatment in the department of urologyFilippenko, N. G.Malorodova, T. N.Pokrovskaya, T. G.Batishchev, S. A.Kulchenkova, T. I.http://dspace.bsuedu.ru/handle/123456789/465992022-05-05T00:31:04Z2017-01-01T00:00:00ZTitle: Approaches to antibiotic therapy in patients with calculous pyelonephritis, undergoing in-patient treatment in the department of urology
Authors: Filippenko, N. G.; Malorodova, T. N.; Pokrovskaya, T. G.; Batishchev, S. A.; Kulchenkova, T. I.
Abstract: To study the structure of pathogens and their sensitivity to antibiotics in patients with calculous pyelonephritis undergoing treatment in the department of urology of St. Joseph Belgorod Regional Clinical Hospital in 2013-2015. To determine the antibacterial chemotherapeutic agents for initial and etiological antibiotic therapy of patients with calculous pyelonephritis in the department of urology of St. Joseph Belgorod Regional Clinical Hospital2017-01-01T00:00:00ZPharmacological efficacy of an inhibitor of arginase-2 KUD975 with L-NAME-induced endothelial dysfunctionKudryavtsev, K. V.Korokin, M. V.Gudyrev, O. S.http://dspace.bsuedu.ru/handle/123456789/465982022-05-05T00:27:41Z2017-01-01T00:00:00ZTitle: Pharmacological efficacy of an inhibitor of arginase-2 KUD975 with L-NAME-induced endothelial dysfunction
Authors: Kudryavtsev, K. V.; Korokin, M. V.; Gudyrev, O. S.
Abstract: The study of endotelio- and cardioprotective activity of finished dosage forms - tablets, film-coated, containing 10 mg of phenolic nature KUD-975, was shown a statistically significant decrease in blood pressure and the coefficient of endothelial dysfunction on the background of simulation L-NAME-induced pathology. In the group of animals treated with KUD975 found a statistically significant increase in the concentrations of stable metabolites of nitric oxide, which in addition to the normalization of vasodilation says about endothelioprotektive action of the compounds studied2017-01-01T00:00:00ZEfficacy and safety of pharmacological treatment of the with clinically apparent bacteriuria and asymptomatic bacteriuria in the pregnant womenLikhikh, D. G.Lazareva, G. A.http://dspace.bsuedu.ru/handle/123456789/465972022-05-05T00:25:25Z2017-01-01T00:00:00ZTitle: Efficacy and safety of pharmacological treatment of the with clinically apparent bacteriuria and asymptomatic bacteriuria in the pregnant women
Authors: Likhikh, D. G.; Lazareva, G. A.
Abstract: The article explores the problem of urinary tract infection in pregnant women. It presents the statistical analysis of the frequency of different forms of urinary tract infection during pregnancy. Our data is compared to the statistics given by other national and international researchers2017-01-01T00:00:00Z