http://dspace.bsu.edu.ru/handle/123456789/46543
Title: | The study of osteoprotective properties of nanoparticulated forms of resveratrol and losartan |
Authors: | Koklina, N. Y. Gudyrev, O. S. Faitelson, A. V. |
Keywords: | medicine pharmacology osteoporosis steoprotective properties endothelial dysfunction bivalos osartan resveratrol |
Issue Date: | 2015 |
Citation: | Koklina, N.Y. The study of osteoprotective properties of nanoparticulated forms of resveratrol and losartan / N.Y. Koklina, O.S. Gudyrev, A.V. Faitelson // Research Result: Pharmacology and Clinical Pharmacology. - 2015. - Vol. 1, № 1(1).- P. 28-33. - Doi: 10.18413/2500-235X-2015-1-4-32-38. - Refer.: p. 32-33. |
Abstract: | The study demonstrated that endothelial dysfunction of bone microvasculature and deterioration of regional blood flow in bone developed eight weeks after ovariectomy in female white Wistar rats thus raising the risk of generalized osteoporosis. Nanoparticulated forms of losartan and resveratrol possessing endothelioprotective action effectively prevented reduction of regional microcirculation in bone tissue through keeping it at the same level as intact rats had |
URI: | http://dspace.bsu.edu.ru/handle/123456789/46543 |
Appears in Collections: | Vol. 1, № 1 |
File | Description | Size | Format | |
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Koklina_The_study.pdf | 580.38 kB | Adobe PDF | View/Open |
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