http://dspace.bsu.edu.ru/handle/123456789/46584| Title: | Molecular docking, ADMET study and in vivo pharmacological research of N-(3,4-dimetoxyphenyl)-2-{[2-methyl-6-(pyridine-2-yl)-pyrimidin-4-yl]thio}acetamide as a promising anticonvulsant |
| Authors: | Severina, H. I. Skupa, O. O. Voloshchuk, N. I. Saidov, N. Bunyatyan, V. A. |
| Keywords: | medicine pharmacology anticonvulsant docking pyrimidine rotarod test acetamide lamotrigine phenobarbital |
| Issue Date: | 2020 |
| Citation: | Molecular docking, ADMET study and in vivo pharmacological research of N-(3,4-dimetoxyphenyl)-2-{[2-methyl-6-(pyridine-2-yl)-pyrimidin-4-yl]thio}acetamide as a promising anticonvulsant / H.I. Severina [et al.] // Research Results in Pharmacology. - 2020. - Vol.6, №2.-P. 27-41. - Doi: 10.3897/rrpharmacology.6.53332. |
| Abstract: | The search for new anticonvulsants for epilepsy treatment with higher efficacy and better tolerability remains important. The aim of the present research was an in silico and in vivo pharmacological study of N-(3,4-dimethoxyphenyl)-2-((2-methyl-6-(pyridin-2-yl)pyrimidin-4-yl)thio)acetamide (Epirimil) as a promising anticonvulsant |
| URI: | http://dspace.bsu.edu.ru/handle/123456789/46584 |
| Appears in Collections: | Vol. 6, № 2 |
| File | Description | Size | Format | |
|---|---|---|---|---|
| Severina_Molecular_20.pdf | 2.61 MB | Adobe PDF | View/Open |
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