http://dspace.bsu.edu.ru/handle/123456789/46653| Title: | Neuropharmacological characteristics of antidepressant action of a new 3-substituted thietane-1,1-dioxide derivative |
| Authors: | Nikitina, I. L. Gaisina, G. G. |
| Keywords: | medicine pharmacology animal outbred strain antidepressants reserpine thietane fluoxetine |
| Issue Date: | 2021 |
| Citation: | Nikitina, I.L. Neuropharmacological characteristics of antidepressant action of a new 3-substituted thietane-1,1-dioxide derivative / I.L. Nikitina, G.G. Gaisina // Research Results in Pharmacology. - 2021. - Vol.7, №3.-P. 63-71. - Doi: 10.3897/rrpharmacology.7.68560. |
| Abstract: | Due to severe burden of depressive disorders and a low rate of remission in patients receiving antidepressant therapy, there is an urgent need for developing novel agents with antidepressant action and a fundamentally new mechanism of action. 3-ethoxythietane-1,1-dioxide (N-199/1) is a new molecule that showed significant antidepressant properties when administered intraperitoneally once or repeatedly. The aim of the present study was to investigate the mechanism of action of N-199/1, using reserpine test |
| URI: | http://dspace.bsu.edu.ru/handle/123456789/46653 |
| Appears in Collections: | Vol. 7, № 3 |
| File | Description | Size | Format | |
|---|---|---|---|---|
| Nikitina_Neuropharmacological.pdf | 2.09 MB | Adobe PDF | View/Open |
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