http://dspace.bsu.edu.ru/handle/123456789/46691| Title: | Validation of structural-based virtual screening protocols with the PDB Code 3G0B and prediction of the activity of Tinospora crispa compounds as inhibitors of dipeptidyl-peptidase-IV |
| Authors: | Andri Prasetiyo Shirly Kumala Esti Mumpuni Raymond R. Tjandrawinata |
| Keywords: | medicine pharmacology antidiabetic DPP-IV inhibitors Tinospora crispa validation Molegro Virtual Docker |
| Issue Date: | 2022 |
| Citation: | Validation of structural-based virtual screening protocols with the PDB Code 3G0B and prediction of the activity of Tinospora crispa compounds as inhibitors of dipeptidyl-peptidase-IV / Andri Prasetiyo [et al.] // Research Results in Pharmacology. - 2022. - Vol.8, №1.-P. 95-102. - Doi: 10.3897/rrpharmacology.8.76237. |
| Abstract: | Brotowali (Tinospora crispa) has been traditionally used as an antidiabetic drug. DPP-IV inhibitor as an antidiabetic will increase insulin secretion. It indirectly escalates incretin hormones, such as Glucagon-Like peptide-1 (GLP-1) which depends on glucose. This study predicts potential compounds from the Brotowali plants, such as DPP-IV inhibitors, using the Molegro Virtual Docker (MVD) |
| URI: | http://dspace.bsu.edu.ru/handle/123456789/46691 |
| Appears in Collections: | Vol. 8, № 1 |
| File | Description | Size | Format | |
|---|---|---|---|---|
| Prasetiyo_Validation.pdf | 1.08 MB | Adobe PDF | View/Open |
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