DC Field | Value | Language |
dc.contributor.author | Chaprov, K. | - |
dc.contributor.author | Rezvykh, A. | - |
dc.contributor.author | Funikov, S. | - |
dc.contributor.author | Ivanova, T. A. | - |
dc.contributor.author | Deykin, A. V. | - |
dc.date.accessioned | 2023-03-14T11:59:36Z | - |
dc.date.available | 2023-03-14T11:59:36Z | - |
dc.date.issued | 2021 | - |
dc.identifier.citation | A bioisostere of Dimebon/Latrepirdine delays the onset and slows the progression of pathology in FUS transgenic mice / K. Chaprov [et al.] // CNS Neuroscience & Therapeutics. - 2021. - Vol.27, №7.-P. 765-775. | ru |
dc.identifier.uri | http://dspace.bsu.edu.ru/handle/123456789/52123 | - |
dc.description.abstract | Avtors developed a CatWalk analysis protocol that allows detection of gait changes in FUS transgenic mice and the effect of DF402 on their gait already at early pre-symptomatic stage. At this stage, a limited number of genes significantly change expression in transgenic mice and for 60% of these genes, DF402 treatment causes the reversion of the expression pattern | ru |
dc.language.iso | en | ru |
dc.subject | medicine | ru |
dc.subject | medical genetics | ru |
dc.subject | ALS mouse model | ru |
dc.subject | drug effects | ru |
dc.subject | FUS | ru |
dc.subject | gamma-carbolines | ru |
dc.subject | motor neuron disease | ru |
dc.subject | TLS | ru |
dc.title | A bioisostere of Dimebon/Latrepirdine delays the onset and slows the progression of pathology in FUS transgenic mice | ru |
dc.type | Article | ru |
Appears in Collections: | Статьи из периодических изданий и сборников (на иностранных языках) = Articles from periodicals and collections (in foreign languages)
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