| DC Field | Value | Language |
|---|
| dc.contributor.author | Krivokolysko, S. G. | - |
| dc.contributor.author | Dotsenko, V. V. | - |
| dc.contributor.author | Bibik, E. Yu. | - |
| dc.contributor.author | Samokish, A. A. | - |
| dc.contributor.author | Venidiktova, Y. S. | - |
| dc.date.accessioned | 2024-03-11T13:45:54Z | - |
| dc.date.available | 2024-03-11T13:45:54Z | - |
| dc.date.issued | 2022 | - |
| dc.identifier.citation | New hybrid molecules based on sulfur-containing nicotinonitriles: synthesis, analgesic activity in acetic acid-induced writhing test, and molecular docking studies / S.G. Krivokolysko, V.V. Dotsenko, Bibik E.Yu. [et al.] // Russian Journal of Bioorganic Chemistry. - 2022. - Vol.48, №3.-P. 628-635. | ru |
| dc.identifier.uri | http://dspace.bsu.edu.ru/handle/123456789/61085 | - |
| dc.description.abstract | New hybrid molecules bearing furyl and 1,4-dihydronicotinonitrile (or 1,4,5,6-tetrahydronicotinonitrile) fragments have been prepared. The analgesic activity was studied in vivo (rats) in acetic acidinduced writhing test. Some compounds showed activity exceeding that of the reference compound (metamizole) | ru |
| dc.language.iso | en | ru |
| dc.subject | chemistry | ru |
| dc.subject | organic chemistry | ru |
| dc.subject | nicotinonitriles | ru |
| dc.subject | 1,4-dihydropyridines | ru |
| dc.subject | 1,4,5,6-tetrahydropyridines | ru |
| dc.subject | analgesics | ru |
| dc.subject | molecular docking | ru |
| dc.title | New hybrid molecules based on sulfur-containing nicotinonitriles: synthesis, analgesic activity in acetic acid-induced writhing test, and molecular docking studies | ru |
| dc.type | Article | ru |
| Appears in Collections: | Статьи из периодических изданий и сборников (на иностранных языках) = Articles from periodicals and collections (in foreign languages)
|
