http://dspace.bsu.edu.ru/handle/123456789/44326
Title: | Synthesis and study of new 2H-pyranoquinolin-2-one-based inhibitors of blood coagulation factors Xa and XIa |
Authors: | Potapov, A. Yu. Paponov, B. V. Podoplelova, N. A. Panteleev, M. A. Polikarchuk, V. A. |
Keywords: | chemistry organic chemistry molecular hybridization 7-hydroxyhydroquinoline 6-carbaldehyde methyl pyrimidine-3-oxopropionate 2H-pyrano[3,2-g]quinolin-2-one |
Issue Date: | 2021 |
Citation: | Synthesis and study of new 2H-pyranoquinolin-2-one-based inhibitors of blood coagulation factors Xa and XIa / Potapov A.Yu. [et al.] // Russian Chemical Bulletin, International Edition. - 2021. - Vol.70, №3.-P. 492-497. |
Abstract: | Condensation of 7-hydroxy-1,2,2,4-tetramethylhydroquinoline-6-carbaldehydes with various hetaryl-substituted 3-oxo esters aff orded a series of hybrid hydro-6,8,8,9-tetramethyl-2H-pyrano[3,2-g]quinolin-2-ones. A number of these compounds exhibited relatively high inhibitory activity against blood coagulation factors Xa and XIa |
URI: | http://dspace.bsu.edu.ru/handle/123456789/44326 |
Appears in Collections: | Статьи из периодических изданий и сборников (на иностранных языках) = Articles from periodicals and collections (in foreign languages) |
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Paponov_Synthesis.pdf | 911.94 kB | Adobe PDF | View/Open |
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