http://dspace.bsu.edu.ru/handle/123456789/64288| Title: | Generation of LEPR knockout rabbits with CRISPR/CAS9 system |
| Authors: | Silaeva, Yu. Yu. Safonova, P. D. Popov, D. V. Filatov, M. A. Gubarev, Yu. D. |
| Keywords: | medicine medical genetics genetically modified rabbits CRISPR/Cas9 LEPR leptin |
| Issue Date: | 2024 |
| Citation: | Generation of LEPR knockout rabbits with CRISPR/CAS9 system / Silaeva Yu.Yu., P.D. Safonova, D.V. Popov [et al.] // Doklady Biological Sciences. - 2024. - Vol.518.-P. 248-255. - Doi: 10.1134/S0012496624600234. - Refer.: p. 255. |
| Abstract: | The LEPR gene encodes a leptin hormone receptor, and its mutations are associated with morbid obesity, dysregulation of lipid metabolism, and fertility defects in humans. Spontaneous Lepr mutations have been described in rodents, and Lepr knockout animals have been generated, in particular, using the CRISPR/Cas9 system |
| URI: | http://dspace.bsu.edu.ru/handle/123456789/64288 |
| Appears in Collections: | Статьи из периодических изданий и сборников (на иностранных языках) = Articles from periodicals and collections (in foreign languages) |
| File | Description | Size | Format | |
|---|---|---|---|---|
| Popov_Generation_24.pdf | 1.38 MB | Adobe PDF | View/Open |
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