http://dspace.bsuedu.ru/handle/123456789/66355| Title: | Regulation of 11β-hydroxysteroid dehydrogenase isoforms: pharmacophore search and molecular design of prospective 11β-HSD1 inhibitors |
| Authors: | Korokin, M. V. Avtina, T. V. Koklin, I. S. Taran, E. I. Kochkarov, A. A. Korokina, L. V. Gudyrev, O. S. Koroleva, N. V. Vasyutkin, V. V. |
| Keywords: | medicine pharmacology osteoporosis 11β-Hydroxysteroid Dehydrogenase regulation 11β-HSD inhibitors drug targets azoloazines |
| Issue Date: | 2025 |
| Citation: | Regulation of 11β-hydroxysteroid dehydrogenase isoforms: pharmacophore search and molecular design of prospective 11β-HSD1 inhibitors / M.V. Korokin, T.V. Avtina, I.S. Koklin [et al.] // Research Results in Pharmacology. - 2025. - Vol.11, №4.-P. 90-101. - Doi: 10.18413/rrpharmacology.11.862. - Refer.: p. 98-100. |
| Abstract: | As a result of this work, original azoloazine derivatives have been developed for further biological testing aimed at regulating the activity of 11β-hydroxysteroid dehydrogenase isoforms (11β-HSDs) for pharmacological correction of bone remodeling and osteoreparation disorders |
| URI: | http://dspace.bsuedu.ru/handle/123456789/66355 |
| Appears in Collections: | Vol. 11, № 4 |
| File | Description | Size | Format | |
|---|---|---|---|---|
| Korokin_Regulation_25.pdf | 855.77 kB | Adobe PDF | View/Open |
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