http://dspace.bsuedu.ru/handle/123456789/66373| Title: | Investigation of imidazole-4,5-dicarboxylic acid derivatives activity on visceral pain in mice |
| Authors: | Yakovleva, E. E. Kamalova, M. T. Yakovleva, V. G. Brusina, M. A. Bychkov, E. R. |
| Keywords: | medicine pharmacology glutamate NMDA-receptor antagonists imidazole-4,5-dicarboxylic acid derivatives analgesic effect visceral pain mice |
| Issue Date: | 2025 |
| Citation: | Investigation of imidazole-4,5-dicarboxylic acid derivatives activity on visceral pain in mice / E.E. Yakovleva, M.T. Kamalova, V.G. Yakovleva [et al.] // Research Results in Pharmacology. - 2025. - Vol.11, №4.-P. 199-204. - Doi: 10.18413/rrpharmacology.11.773. - Refer.: p. 203-204. |
| Abstract: | Experimental studies on rodents have shown that mGluR1 receptor inhibitors demonstrate antinociceptive potential in acute pain models. New ligands of the glutamate NMDA-receptor complex are imidazole-4,5-dicarboxylic acid derivatives, which conformational rigidity allows increasing selectivity interaction and decreasing a number of side effects with the implementiation a high analgesic potential |
| URI: | http://dspace.bsuedu.ru/handle/123456789/66373 |
| Appears in Collections: | Vol. 11, № 4 |
| File | Description | Size | Format | |
|---|---|---|---|---|
| Yakovleva_Investigation_25.pdf | 433.59 kB | Adobe PDF | View/Open |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.