Evaluation of pharmacological correction of hypoxic-ischemic encephalopathy sequelae using peptide erythropoietin analogs in a mouse model of mild and moderate hypoxic-ischemic encephalopathy during the late remodeling phase

Abstract

In this experimental study, Epobis and Ara-290 normalized mild HIE hyperlocomotion in the open field, whereas EPO mainly improved anxiety-like behavior and only Epobis increased peripheral time toward intact levels